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Thursday, March 19, 1998

It’s in the genes, but UCLA is where it’s at

GENETICS: "Engineering

the Human Germline" to be held Friday in Schoenberg

By Kathryn Combs

Daily Bruin Staff

Building a better human? With the recent controversy surrounding
cloning, the realization of genetic engineering may lie just over
the horizon.

And according to the organizers of "Engineering the Human
Germline," a free symposium being offered at UCLA on Friday, these
kinds of medical technologies may not be as far away as many
think.

"I don’t think many understand how powerful this is," said Dr.
Lee Silver, professor of genetics at Princeton University and a
scheduled speaker at the symposium.

"Most people, I think, don’t yet appreciate that we are going to
be able to modify human beings."

Dr. Gregory Stock, a symposium organizer and director of the
Science, Technology and Society Program with UCLA’s Center for the
Study of Evolution and the Origin of Life, said genetic engineering
has already been realized on the level of individual cells but
that, "you can imagine a lot more things that you can do with
somatic engineering."

"As we get into more sophisticated things we will probably end
up using germline engineering," Stock said.

Germline engineering involves the alteration of DNA in the egg
or sperm cell, while somatic engineering involves the alteration of
DNA in the individual cells. Changes made in the egg and sperm
cells cause traits to be transmitted to future generations.

"(This) is the ultimate way that genetic information is going to
provide benefits to people," said Dr. John Campbell, professor of
neurobiology and co-organizer for the symposium.

"One reason for (holding the conference now) is so that we can
layout the factual and conceptual basis for it before the
controversy overwhelms us like what happened with cloning,"
Campbell said.

Among topics that are scheduled to be discussed at the symposium
are ethics and safety, in-vitro fertilization and the battle
against disease.

The symposium will be held Friday from 9:00 a.m. to 5:30 p.m. in
Schoenberg Hall. Admission is free and the event is open to the
public.

For more information, contact the UCLA Study for the Center of
Evolution and the Origin of Life at (310) 825-1769 or visit their
web site at www.ess.ucla.edu/huge.

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